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CoBaDex CZS (Zinc and Selenium) Tablets

INDICATIONS Cobadex CZS is indicated as nutritional adjuvant in management of diabetes mellitus. For diabetic patients with known nutritional deficit or at risk of developing nutritional deficiency.Cobadex CZS is to be co-prescribed for oral administration with oral anti-diabetic agents and insulin injections.

CoBaDex CZS (Zinc and Selenium) tablets

Active ingredients

Each film-coated tablet contains:

• Pyridoxine Hydrochloride IP 3 mg

• Nicotinamide IP 100 mg

• Cyanocobalamin IP 15 meg

• Folic Acid IP 1500 meg

• Chromium Picolinate USP 250 meg

• Selenious Acid USP equal to elemental Selenium 100 meg

• Zinc Sulfate Monohydrate USP 61.8 mg (equivalent to 22.5 mg of elemental Zinc) (Appropriate overages added)

• Colours: Titanium Dioxide IP, Lake Ponceau 4R. and Lake Carmoisine.

INDICATIONS

Cobadex CZS is indicated as nutritional adjuvant in management of diabetes mellitus. For diabetic patients with known nutritional deficit or at risk of developing nutritional deficiency.Cobadex CZS is to be co-prescribed for oral administration with oral anti-diabetic agents and insulin injections.

Conditions where dietary restrictions may lead to deficiency states include peptic-ulcer, obesity, hypertension, chronic diarrhoea and dysentery, malnutrition and inadequate diet.

Cobadex CZS is also indicated as vitamin supplement during pregnancy and lactation.

In illness and to increase resistance against infection. It has been found of value in clinical and sub-clinical vitamin deficiency states such as megaloblastic anaemia, diarrhoea. Supplementation of diet in old age and as an aid to recovery from illness.

CLINICAL PHARMACOLOGY

Vitamins are essential for normal metabolic functions including hematopoiesis.

Vitamin B complex forms part of coenzymes essential for the metabolism of proteins, carbohydrates and fatty acids.

Folic acid is needed for normal cell growth. Folic acid and cyanocobalamin are metabolically interrelated. They are essential to nucleic acid synthesis and normal maturation of red blood cells.

Nicotinamide serves as a coenzyme in oxidation - reduction reactions in tissue respiration.

Trace elements are required for various metabolic processes.

Chromium, Zinc and Selenium (CZS) are trace elements essential for normal biochemical processes. In diabetes mellitus type I and type II lack or absence of insulin is the fundamental defect. The CZS elements are integral to normal insulin action.

Chromium is an necessary trace constituent that potentiates insulin metabolism thus manipulating lipid, carbohydrate, and protein actions.

Zinc is the metal component or activator of many enzymes in the body. Its availability governs the tissue concentration and activities of certain metallo enzymes and the rate of synthesis of the nucleic acids and protein, thereby influencing tissue growth and reparative process.

Selenium is an essential trace element and is an integral part of the enzyme system glutathione peroxidase; this enzyme protects intracellular structure against oxidative damage.

CONTRA-INDICATIONS

Hypersensitivity to any of the ingredients.

DOSAGE AND ADMINISTRATION Adults: One tablet daily.

PHARMACEUTICAL PRECAUTIONS

Store at a temperature not exceeding 30°C, protected from direct sunlight.

Keep out of reach of children.

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Comments (3)
dilip ponkshe

Is this cobadex czs tablet is suitable for type II diabetec patient? whether any wight gain is also noticed.

Regards

D.S.Ponkshe

Does cobadex czs give weight gian?

Does we gain weight if we take cobadex czs

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